IRM Associate Director, Nancy Speck, PhD, Presented with 2015 Henry M. Stratton Medal Recognizing Contributions to Basic Hematology Research

The American Society of Hematology (ASH) awarded Nancy Speck, PhD, IRM Associate Director and Cell and Developmental Biology Department Chair at the Perelman School of Medicine at the University of Pennsylvania, the 2015 Henry M. Stratton Medal for Basic Science for her “seminal contributions in the area of hematology research” over the summer.

Dr. Speck accepted her award on Tuesday, December 8 during the 57th ASH Annual Meeting and Exposition in Orlando.

She also co-leads the Hematologic Malignancies Program at Penn’s Abramson Cancer Center and is an investigator at the Abramson Family Cancer Research Institute.

“I’m very grateful to ASH for bestowing this huge honor on me,” Speck said. “However this recognition also belongs to all of the wonderful students and postdocs I’ve had the privilege to work with during my career.”

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ASH Press Release

Gene Pair Plays Crucial Role in Colon Cancer, Penn Vet Team Shows

Colon cancer is one of the leading causes of cancer-related deaths worldwide, and researchers are hard at work to understand the disease’s complex molecular underpinnings. In a new study out this month in the journal Cell Reports, researchers from the University of Pennsylvania describe two related genes in the Musashi family that are required for colon cancer to develop, and that may be useful targets for effective treatment.

The work, led by Christopher Lengner, an assistant professor in the Department of Biomedical Sciences in Penn’s School of Veterinary Medicine, challenges a paradigm in the field whereby activation of a molecular signaling cascade known as the Wnt pathway is held responsible for the majority of colon cancer cases in humans. The new findings suggest that the Musashi genes, MSI1 and MSI2, act in a path parallel to the Wnt pathway and may be equally important for driving colon cancer.

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