Advances in MSK Regeneration: Oct 22
Oct 7 @ 11:00 am – 12:00 pm
Convergent Mechanisms for Building and Breaking the Gut Barrier
Nov 15 @ 10:30 am – 5:00 pm




The IRM will host our fall symposium, Convergent Mechanisms for Building and Breaking the Gut Barrier, on Tuesday, November 15, 2022 in the Smilow Center for Translational Research Rubenstein Auditorium and Commons. This in person event will explore several facets of the critical gut barrier niche, including the stem cell identities and developmental pathways that comprise the barrier, barrier regeneration, and the role of stem cells in malignant transformations.

We invite trainees to submit abstracts for posters and lightning talks!

Need directions to Smilow? Click here.


Download a PDF version of our schedule.


  • Linda Samuelson, PhD (University of Michigan)
  • Kelley Yan, MD, PhD (Columbia)
  • Klaus Kaestner, PhD (Penn)
  • Mike Verzi, PhD (Rutgers)
  • Nicole Belle, MD, PhD (Penn)
  • Maayan Levy, PhD (Penn)
  • Luke Dow, PhD (Cornell)
  • Omer Yilmaz, MD, PhD (MIT)


Students and postdocs: we are looking for lightning talk and poster presenters! Lightning talks are 90 second, 1 slide “pitches” of your work to the gathered audience. If you are conducting research into an area related to our symposium theme, submit an abstract to by Friday, Nov 4 at 5 PM. Abstracts must include a title, authors and affiliations, and no more than 250 words describing the research.

Posters from trainees studying topics related to the symposium theme are welcome! Please submit your name, affiliations, authors, and title to by Friday, Nov 4 at 5 PM. You do not need to submit a full abstract unless you wish to be considered for a lightning talk.


Thank you to our generous sponsors:

The mission of the Center for Molecular Studies in Digestive and Liver Diseases (CMSDLD) is to unite investigators with interests in digestive and liver disease in the exploration of creative experimental approaches as well as to stimulate others to enter these areas of research. The scientific focus of the Center revolves around host-environmental interactions in digestive and liver disease research from bench to bedside.
The Gastrointestinal Epithelium Modeling (GEM) Program is a collaborative research effort designed to accelerate discovery and innovation using patient-derived organoids (PDO). The GEM Program supports bi-directional, bench-to-bedside research with the goal of developing new therapies for pediatric gastrointestinal diseases. As part of the Division of Gastroenterology, Hepatology and Nutrition, the GEM Program is comprised of scientists and clinicians committed to investigating the pathophysiology of diseases including eosinophilic esophagitis (EoE), inflammatory bowel disease (IBD), Hirschsprung disease and celiac disease.
STEMCELL Technologies provides high-quality cell culture media, cell separation technologies, instruments, accessory products, and educational resources to scientists around the world working on stem cell, immunology, cancer, regenerative medicine, and cellular therapy research. STEMCELL Technologies is dedicated to improving lives through advanced knowledge and scientific discovery, through their commitment to fostering diversity and inclusion in STEM and the life sciences industry, and through investments in sustainability, community, and social responsibility.











Annual IRM Retreat 2023 @ Franklin Institute
Jan 24 @ 12:00 pm – 5:00 pm




The annual IRM retreat will be held on January 24, 2023 from 12-5 PM (with happy hour to follow) at the Franklin Institute Museum of Science in Philadelphia! We hope to see you all for this in-person­ afternoon of highlights from IRM labs, discussion about future research initiatives, and welcoming of new IRM faculty. The IRM retreat is open to any faculty, staff, postdocs, and students from Penn/CHOP interested in regenerative medicine research.


The Franklin Institute is located at 222 N 20th St, Philadelphia, PA 19103. Complete information about directions and ways to get there are posted on the FI website.

If you’re driving, parking is available at the FI’s garage at a cost of $20. The GPS location is 271 North 21st Street
Philadelphia, PA 19103


Students and postdocs: we are looking for lightning talk and poster presenters!

Lightning talks are 90 second, 1 slide “snapshots” of your work to the gathered audience. If you are interested, submit an abstract via email to Rutvi, by 5 PM on Monday, January 16Abstracts must include a title, authors and affiliations, and no more than 250 words describing the research. Any topic related to the broad themes of stem cell biology, tissue engineering, and regenerative medicine is welcome!

If you are interested in presenting a poster, email your name, poster title, and affiliations via email Rutvi, by 5 PM on Monday, January 16. Poster presenters do not need to submit abstracts unless you are interested in being selected for a lightning talk spot.





2nd Annual Ralph L. Brinster Symposium & Elaine Redding Brinster Prize @ Smilow Center for Translational Research
Mar 15 @ 9:00 am – 4:00 pm

The Elaine Redding Brinster Prize in Science or Medicine recognizes foundational discoveries in the fields of biological science and medicine. The Prize— a medal, a citation, and a monetary award of $100,000—is awarded annually to an individual from any country to recognize their outstanding discovery for its unique impact on biomedicine. This year, we are honoring Huda Y. Zoghbi, MD of Baylor College of Medicine for her fundamental contributions to the basis for neurological disorders.

The Ralph L. Brinster Symposium is an annual scientific symposium, held in conjunction with the Prize, to highlight breakthrough science across the entire spectrum of biomedical research. The Symposium, co-sponsored by the Deans of the School of Veterinary Medicine and Raymond and Ruth Perelman School of Medicine, features presentations from extraordinary scientists who rank among the leaders in their fields.

This year, we are thrilled to host a symposium of talks by these eminent scientists:

  • Janet Rossant, PhD, Senior Scientist Emeritus, Hospital for Sick Children; University Professor Emeritus, Department of Molecular Genetics, University of Toronto
    • “Stem Cells, Embryos and Embryo Models”
  • Lynne Maquat, PhD, J. Lowell Orbison Endowed Chair and Professor, Departments of Biochemistry & Biophysics, Oncology, and Pediatrics, School of Medicine and Dentistry; Director, Center for RNA Biology; Chair, Graduate Women in Science, University of Rochester
    • “Mis-regulation of Nonsense-Mediated mRNA Decay in the Intellectual Disability Fragile X Syndrome”
  • Robb Krumlauf, PhD, Investigator & Scientific Director Emeritus, Stowers Institute for Medical Research
    • “Evolution of Hox Proteins: Regulating Pluripotency and Differentiation”
  • Lorenz Studer, MD, Founding Director, Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center
    • “Directing Cell Fate, Maturation, and Age in Human Pluripotent Stem Cells”
  • Huda Y. Zoghbi, MD, Investigator, Howard Hughes Medical Institute, Distinguished Service Professor, Baylor College of Medicine, Director, Jan and Dan Duncan Neurological Research Institute, Texas Children’s Hospital & winner of the Elaine Redding Brinster Prize
    • “Molecular Neurobiological Studies in Rett Syndrome and MECP2 Disorders”

The Elaine Redding Brinster Prize and Ralph L. Brinster Symposium are generously funded by endowments provided by the children of Elaine Redding Brinster and Ralph Brinster.

Need directions to Smilow? Click here.


Download a PDF version of our schedule.