In a newly published paper in Science, IRM member Patrick Seale and others reveal a new discovery regarding the process by which mesenchymal progenitor cells create new adipocytes. Using single-cell RNA sequencing, Seale and colleagues identified a hierarchy involving progenitor cells that express a protein (DPP4) which gives rise to two distinct types of adipocytes. This finding has potential therapeutic applications in treating some metabolic diseases. Read more at Science…
