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Inaugural Elaine Redding Brinster Prize Awarded to Scientist Who Sparked Growth of Epigenetics

The Institute for Regenerative Medicine the University of Pennsylvania has awarded C. David Allis, PhD, an American molecular biologist, with the inaugural Elaine Redding Brinster Prize in Science or Medicine. Allis’ research helped spark the field of epigenetics, which is the study of how a person’s behavior and environment can change the way their genes … Continue reading Inaugural Elaine Redding Brinster Prize Awarded to Scientist Who Sparked Growth of Epigenetics

Penn Medicine Awarded $6 Million to Advance Understanding of Human Genome Function in Health and Disease

The National Institutes of Health (NIH) has selected Penn Medicine as one of 25 award recipients across 30 sites in the United States to serve as Impact of Genomic Variation on Function (IGVF) investigators, with the goal of better understanding how genetic differences impact how human genes function, and how these variations influence human health … Continue reading Penn Medicine Awarded $6 Million to Advance Understanding of Human Genome Function in Health and Disease

Putting a spotlight on microscopy outreach

Scientists use microscopes to see things that are normally hidden. But how can these tools be used to show people the world of science and discovery? Recently, Development featured the voices of 5 science educators who use microscopes to “reveal new worlds,” “improve our communication and understanding of developmental biology,” and “break down barriers and … Continue reading Putting a spotlight on microscopy outreach

Experimenting with stem cells at the bench

Working to find cellular cures for diseases.

The IRM supports initiatives to translate discoveries in stem cell science into new therapies. We offer:

  • Collaborative Research Programs
  • Grants for Innovative Ideas
  • Engaging Symposiums & Events
  • Training Workshops
  • Award-winning Outreach Partnerships
  • Scientific Communication Support

Research Programs

Epithelial Stem Cells

The cells that constitute our skin and line our organs are the first line of defense against injury and illness. These vital barriers are replenished by epithelial stem cells. IRM researchers study epithelial stem cells throughout the body to find ways to improve wound healing, heal the lungs after viral infection, reverse baldness, and more. … Continue reading Epithelial Stem Cells

Hematopoietic Stem Cells

Humans produce hundreds of billions of blood cells every day, thanks to the incredible regenerative potential of hematopoietic stem cells (HSCs). To create all those oxygen-carrying red blood cells and pathogen-fighting white blood cells, HSCs follow very specific development pathways. IRM researchers are exploring how to control these pathways and use HSCs to treat disease. … Continue reading Hematopoietic Stem Cells

Musculoskeletal Regeneration

Muscles, bones, and cartilage are critical to our quality of life, so maintaining musculoskeletal health from childhood to old age is incredibly important. However, injuries, aging, and disease can all undermine musculoskeletal health. IRM scientists and engineers are studying innovative ways to repair degraded tissues and are working toward solutions for muscular dystrophy, osteoarthritis, and … Continue reading Musculoskeletal Regeneration

Neurodevelopment & Regeneration

The nervous system’s capacity for growth and change underlies everything from proper mental development to the body’s coordination and movement. IRM researchers study how neurons develop in different stages of life, why the neurons in limbs regenerate better than in the brain, and how dysregulation leads to diseases including autism spectrum disorder, schizophrenia, and glioblastoma. … Continue reading Neurodevelopment & Regeneration

Reproductive Medicine

The cells of the reproductive system give rise to all other cells in the body. IRM researchers seek to understand the regenerative qualities of sperm and eggs and the biology of early embryos, with the goals of improving the storage of germ cells and embryos for cancer patients and creating safe, effective assisted reproductive technologies. … Continue reading Reproductive Medicine

Outreach

Sharing our science across the Philadelphia region and beyond.