• The Institute for Regenerative Medicine is based in the Smilow Center for Translational Research and extends across UPenn’s campus.

  • The links between medicine, engineering and veterinary science differentiate Penn’s Institute for Regenerative Medicine from other stem cell Institutes across the country.

  • The IRM promotes discoveries in stem cell biology and regeneration to generate new therapies that may alleviate suffering and disease.

  • When our interdisciplinary research and programs bring together individuals with broad interests and diverse backgrounds, our collaborations lead to greater advances.

  • Stem cell research is critical to developing new skin tissues and, ultimately, changing the way we care for devastating wounds.

  • At Penn, we’re discovering real possibilities of future treatments for cardiac disease because we have the research and clinical expertise to make it happen.

Institute For Regenerative Medicine
  • Featured Stories

    It’s been a busy and productive year for the IRM and its faculty members, including two dynamic and interdisciplinary symposia, an impressive roster of guest speakers, events that engage our students and trainees, and, of course, the research that our members conduct on a daily basis. Below are some of the outstanding highlights from the multiple papers published by our…

  • Featured Stories

    In a newly published paper in Science, IRM member Patrick Seale and others reveal a new discovery regarding the process by which mesenchymal progenitor cells create new adipocytes. Using single-cell RNA sequencing, Seale and colleagues identified a hierarchy involving progenitor cells that express a protein (DPP4) which gives rise to two distinct types of adipocytes. This finding has potential therapeutic…

  • Featured Stories

    In a recent study published in Cell, IRM faculty members Guo-Li Ming and Hongjun Song have discovered that a specific type of stem cell generates new neurons – a finding that could lead to a better understanding of degenerative neurological conditions and injuries, as well as to therapeutic developments in managing those conditions. Click here to read more at Penn…